Tadalafil — what it does and how to use it

Tadalafil can last up to 36 hours — that’s why people call it the "weekend pill." If you’re curious about tadalafil, this page gives clear, practical info: what it treats, how to take it, common side effects, and safe buying tips.

Tadalafil is a PDE5 inhibitor used mainly for erectile dysfunction (ED). It also treats benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension under different brand names. The active drug is the same whether you see "Cialis" or generic tadalafil—what matters is dose, timing, and safety.

How to dose tadalafil

There are two common ways people take tadalafil. First, on-demand dosing: typical single doses are 10 mg or 20 mg taken at least 30 minutes before sexual activity. Food doesn’t reduce its effectiveness much, but a heavy high‑fat meal can slow the start.

Second, daily dosing: low daily doses (usually 2.5 mg or 5 mg) are taken once every day and suit people who want more spontaneity. Daily dosing is also the usual choice when treating BPH symptoms. Follow your doctor’s instructions—don’t mix on-demand and daily regimens without a doctor’s advice.

Onset varies: some feel effects in 30–60 minutes, while for others it may take longer. The drug’s action can last up to 36 hours, but that doesn’t mean a constant erection—rather, the body responds to sexual stimulation during that window.

Safety tips and warnings

Common side effects include headache, flushing, indigestion, back pain, and muscle aches. These usually pass within a day. Seek urgent care if an erection lasts more than 4 hours (priapism), or if you have sudden vision loss or hearing changes.

Do not take tadalafil with nitrates (often prescribed for chest pain). The combo can cause a dangerous drop in blood pressure. Tell your doctor about all meds you take—especially alpha‑blockers, some blood pressure drugs, and certain antifungal or antibiotic medicines that raise tadalafil levels.

People with severe heart disease, recent stroke or heart attack, very low blood pressure, or certain eye problems should avoid tadalafil unless a doctor approves it. Dose adjustments may be needed for liver or kidney impairment.

Buying online? Only use licensed pharmacies that require a prescription. Cheap pills from unknown sites can be fake or contaminated. Generic tadalafil is safe when sourced from reputable pharmacies and properly labeled.

Practical tips: start at a low dose to see how you react, avoid heavy drinking when you plan to take the pill, store tablets at room temperature, and keep a list of your medicines to show your prescriber. If you’re unsure whether tadalafil is right for you, a simple chat with your doctor or pharmacist will clear it up fast.