If you’re looking at a prescription for Zoloft, the first question on most people’s minds is the price. The cost can swing a lot depending on where you buy it, whether you have insurance, and if you’re using the brand name or the generic version, sertraline. Below we break down the biggest factors that decide the price and give you easy ways to keep the bill low.
Zoloft is the brand name for sertraline, an SSRI used for depression, anxiety, and a few other conditions. In 2025 the brand‑name pill regularly sits between $150 and $250 for a 30‑day supply in the U.S. The generic version, however, can be as cheap as $10‑$30 for the same amount. The price difference is mainly due to branding, marketing costs, and the fact that many insurers list the generic on their formularies first.
Most health plans cover sertraline, but the co‑pay you see can vary. A high‑deductible plan might ask you to pay the full price until the deductible is met, while a low‑deductible plan could charge just $5‑$15 per month. If you shop at big‑box pharmacies (like CVS or Walgreens) you’ll often find the same generic priced similarly, but some discount chains (such as Walmart) can offer it for under $5.
Online pharmacies add another layer of savings. Reputable sites that require a prescription often have bulk‑buy agreements and can list a 30‑day supply of generic sertraline for $4‑$8. Make sure the pharmacy is licensed, shows a physical address, and provides a pharmacist’s contact info before you order.
Coupons and manufacturer coupons also trim costs. The maker of Zoloft sometimes offers a $20‑$30 discount for new patients, which can bring the brand name down to about $120 for a month’s supply. If you’re already on a stable dose, the generic is still the cheaper choice.
For people without insurance, the best bet is to ask the doctor to write a prescription for the generic. Most pharmacies will gladly switch you over at the counter if you ask. Some clinics even have in‑house pharmacies that sell sertraline for $8‑$12 per month.
Finally, keep an eye on price‑comparison tools. Websites like GoodRx let you type in “sertraline 100mg” and see a list of nearby pharmacy prices, often showing a printable coupon that drops the cost further.
Bottom line: the price you pay for Zoloft isn’t set in stone. By choosing generic sertraline, checking your insurance formulary, using reputable online pharmacies, and hunting for coupons, you can usually stay under $30 a month. If you need the brand name for any reason, discount programs can still shave off a good chunk of the bill. Stay informed, compare prices, and you’ll keep your treatment affordable without sacrificing quality.
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